Long-Lasting Relief for Knee Osteoarthritis: How a Single Arthrosamid Injection Restores Confidence to Move

Introduction
Knee osteoarthritis (knee OA) is a common and often life-altering condition impacting millions worldwide. It causes pain, stiffness, and reduced mobility, making everyday activities—like walking, climbing stairs, or doing housework—challenging. For many, this loss of comfort and ease can be disheartening, leading to reduced confidence in staying active. Thankfully, new innovations bring renewed hope. This article explores how a single Arthrosamid injection can offer lasting relief, helping people with knee OA regain their comfort and, most importantly, the confidence to move freely once again.

What Is Knee Osteoarthritis and How Does It Affect Daily Life?

Knee osteoarthritis happens when the cartilage protecting the ends of the bones in the knee joint wears down over time. This damage leads to pain, swelling, and stiffness, which can make movement difficult and uncomfortable. In the UK, around one in five people over 45 is impacted, showing just how widespread knee OA truly is.

Symptoms often start small—perhaps a little morning stiffness or some pain after physical activity—but typically worsen over time. Everyday tasks like walking short distances, climbing stairs, or handling household chores can gradually become more difficult, eroding both independence and overall quality of life. Traditional treatments such as painkillers, physical therapy , and steroid injections are available, but their effects can be short-lived, and many people continue to struggle with ongoing symptoms.

How Does Arthrosamid Help?

Arthrosamid is a modern treatment developed to address knee OA symptoms in a minimally invasive way. It’s a clear, water-based gel containing a special polymer called polyacrylamide that is both safe and long-lasting when placed inside the knee.

Delivered as a single injection directly into the joint, Arthrosamid coats and cushions the lining of the knee (the synovial membrane). It acts as a soft, shock-absorbing cushion, helping to reduce friction and improve joint lubrication. Because Arthrosamid is designed to stay securely in the joint, it can provide pain relief and improve movement for up to two years—meaning far fewer repeat treatments.

Clinical studies support these lasting benefits. Results show that people experience significantly less pain and improved function for one to two years after the injection. Arthrosamid doesn’t just ease symptoms in the short-term; it provides ongoing relief from just one treatment.

What Do Patients Say About Arthrosamid?

Research and patient experiences both support the benefits of Arthrosamid . Clinical studies show that people treated with Arthrosamid report significant pain relief and better knee function, measured by standard tools like the Visual Analog Scale (VAS) and the Oxford Knee Score, for up to two years.

Safety is also a key strength; studies report no long-term side effects. Interestingly, research suggests that older adults, those with milder arthritis changes, and people without diabetes tend to see the greatest improvements.

Beyond the statistics, many patients share stories of regaining the ability to walk comfortably, manage their homes, and return to hobbies they enjoy. This type of sustained relief often goes beyond easing pain—it also builds confidence and independence, making day-to-day life much more fulfilling.

Expert Views: Insights from Professor Paul Lee and MSK Doctors

Professor Paul Lee , an expert in orthopaedics and rehabilitation, notes that selecting the right patients is crucial to achieving the best results with Arthrosamid . At MSK Doctors, a clinic focused on musculoskeletal health , patients receive comprehensive support throughout their treatment journey.

Experts agree that Arthrosamid is most effective when used as part of a broader, individualised care plan. It works best alongside strategies like physiotherapy , lifestyle changes, and other appropriate treatments. Safety is always a priority, so Arthrosamid is not suitable for people with joint infections or certain other health issues. While it isn’t a replacement for surgery in severe cases, Arthrosamid can help many people delay or avoid the need for more invasive treatments.

Using Arthrosamid as Part of a Complete Osteoarthritis Care Plan

To get the most benefit, healthcare professionals carefully select the people who are likely to respond best to Arthrosamid —typically those with ongoing knee pain but no joint infections. After the injection, a brief period of rest is recommended before gradually resuming physiotherapy and light activity. This supports recovery and helps strengthen the muscles around the knee.

Arthrosamid fits well with other treatments such as tailored exercise, weight management, and appropriate pain relief. Together, these approaches help people with knee OA stay active, independent, and comfortable for as long as possible.

Conclusion
A single Arthrosamid injection offers a long-lasting, effective option for managing knee osteoarthritis . By cushioning the knee and reducing pain and stiffness, it helps restore comfort and renews confidence to enjoy daily life with fewer worries. If you’re considering this treatment, speak with a qualified healthcare professional to find out if Arthrosamid might be right for you.

References

1. Arthrosamid 12.0 Patient Brochure, Contura International, 2024
2. Bliddal et al., ‘Polyacrylamide Hydrogel vs Hyaluronic Acid in Knee Osteoarthritis,’ Bone & Joint Journal, 2023
3. Cole, A., Maulana, R. K., Whitehead, J. P., & Lee, P. Y. F. (2022). A Systematic Review of the Novel Compound Arthrosamid Polyacrylamide (PAAG) Hydrogel for Treatment of Knee Osteoarthritis. Medical Research Archives, 10(8). https://doi.org/10.18103/mra.v10i8.2950
4. Clinical data summary from MSK Doctors and Professor Paul Lee patient outcomes
5. Gao, H. C. K., Akhtar, M., Creedon, C., Nar, Ö. O., & Lee, P. Y. (2025). THE IMPACT OF PATIENT FACTORS ON THE MINIMAL CLINICALLY IMPORTANT DIFFERENCE OF ARTHROSAMID POLYACRYLAMIDE HYDROGEL INJECTION FOR KNEE OSTEOARTHRITIS: A COHORT STUDY. Osteoarthritis and Cartilage, . https://doi.org/10.1016/j.joca.2025.02.648